Ion selective electrode
The use of ion-sensitive electrodes (ISEs) for determination of the concentration or the activity of ions in aqueous media has been known for a long time. An ion-selective electrode (ISE) is an electrode which exhibits an electrical response which is a function of concentration of a specific ion contained in a solution which is in contact with the ISE and a reference electrode. Ion selective electrodes operate on the basis of the Nernst principle which defines a logarithmic relationship between the potential of a solution and its ionic concentration. An ion selective electrode responds selectively to an ion for which the electrode is designed to analyze and is used to measure ion concentrations, ion activities, etc. The determination of a given ion's concentration in a solution is based on the fact that within certain limits the potential of the electrode is directly proportional to the logarithm of the ion's activity. Ion selective electrode sensors that can measure the activity or concentration of analyte ions and metabolites are useful in the analysis of biological fluids including blood, urine, plasma, saliva, spinal fluid, and serum. An ion selective electrode apparatus usually comprises an ion selective electrode and a reference electrode. The ion selective electrode includes an ion selective membrane on the surface of it.
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